SDR

Second-degree relative. The aunts, uncles, grandparents, grandchildren, nieces, nephews, or half-siblings of an individual. Also called second-degree relative. (NCI Thesaurus)

Second-degree relative

SDR. The aunts, uncles, grandparents, grandchildren, nieces, nephews, or half-siblings of an individual. Also called SDR. (NCI Thesaurus)

FDR

First-degree relative. The parents, siblings, or children of an individual. Also called first-degree relative. (NCI Thesaurus)

First-degree relative

FDR. The parents, siblings, or children of an individual. Also called FDR. (NCI Thesaurus)

PCR

Polymerase chain reaction. A procedure that produces millions of copies of a short segment of DNA through repeated cycles of: (1) denaturation, (2) annealing, and (3) elongation. PCR is a very common procedure in molecular genetic testing and may be used to generate a sufficient quantity of DNA to perform a test (e.g., allele-specific amplification, trinucleotide repeat quantification). Also called polymerase chain reaction. (NCI Thesaurus)

Polymerase chain reaction

PCR. A procedure that produces millions of copies of a short segment of DNA through repeated cycles of: (1) denaturation, (2) annealing, and (3) elongation. PCR is a very common procedure in molecular genetic testing and may be used to generate a sufficient quantity of DNA to perform a test (e.g., allele-specific amplification, trinucleotide repeat quantification). Also called PCR. (NCI Thesaurus)

Novel mutation

A newly discovered, distinct gene alteration; NOT the same as new or de novo mutation.

Ashkenazi Jews

One of two major ancestral groups of Jewish individuals, comprised of those whose ancestors lived in Central and Eastern Europe (e.g., Germany, Poland, Russia). The other group is designated Sephardic Jews and includes those whose ancestors lived in North Africa, the Middle East, and Spain. Most Jews living in the United States are of Ashkenazi descent. (NCI Thesaurus)